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Antigenic Specificity | SPAG8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau. Involved in the acrosome reaction and in binding of sperm to the zona pellucida. Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis (PubMed:19548270). May play a role in fertility and microtubule formation through interaction with RANBP9 (PubMed:10500252). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human SPAG8 (NP 758516.1). |
Other Names | [SMP1; BS-84; CT142; HSD-1; SPAG3; CILD28; hSMP-1] |
Gene, Accession # | [SPAG8], NCBI: NP_758516, UniProt: Q99932 |
Catalog # | MBS8548525 |
Price | $280 |
Order / More Info | SPAG8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |