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Antigenic Specificity | EHMT1 (C-term), 1145-1174 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EHMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1145-1174 amino acids from the C-terminal region of human EHMT1. EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle. |
Immunogen | n/a |
Other Names | [Histone-lysine N-methyltransferase EHMT1; 211-; Euchromatic histone-lysine N-methyltransferase 1; Eu-HMTase1; G9a-like protein 1; GLP; GLP1; Histone H3-K9 methyltransferase 5; H3-K9-HMTase 5; Lysine N-methyltransferase 1D; EHMT1; EUHMTASE1; GLP; KIAA1876; KMT1D] |
Gene, Accession # | [EHMT1], Gene ID: 79813, NCBI: NP_001138999.1, UniProt: Q9H9B1 |
Catalog # | MBS9210199 |
Price | $165, $370 |
Order / More Info | EHMT1 (C-term), 1145-1174 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ogawa H.,Science 296:1132-1136(2002). Ota T.,Nat. Genet. 36:40-45(2004). Nagase T.,DNA Res. 8:85-95(2001). |