Edit |   |
---|---|
Antigenic Specificity | BID |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BID Polyclonal Antibody detects endogenous levels of BID protein. BID encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. BH3-interacting domain death agonist is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves BH3-interacting domain death agonist, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. |
Immunogen | Immunogen: Synthesized peptide derived from human BID around the non-phosphorylation site of S78 |
Other Names | [Rabbit BID; BID; BH3-interacting domain death agonist; p22 BID; BID] |
Gene, Accession # | [BID], Gene ID: 637, NCBI: NP_001187.1, UniProt: P55957 |
Catalog # | MBS9701500 |
Price | $130, $220, $325 |
Order / More Info | BID Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |