Human DESMIN (C-TERMINAL) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human DESMIN (C-TERMINAL) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human DESMIN (C-TERMINAL) |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | bovine (expected from sequence), dog (expected from sequence), mouse, porcine (expected from sequence), rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 0.5 mg/ml |
| Applications | ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Goat anti Human Desmin antibody recognizes an epitope within the C-terminal (CT) region of human Desmin, a type III intermediate filament (IF), localized near the Z line in sacromeres of skeletal, smooth and cardiac muscle tissue. Desmin plays an essential role in the architecture of muscle cells, connecting the Z-disk to the subsarcolemmal cytoskeleton, and the contractile apparatus to the, mitochondria, cell nucleus and post-synaptic areas of motor endplates. Desmin is an early indicator for muscle tissue in embryogenesis, and a marker for tumours of myogenic origin. Mutations in the Desmin gene, are responsible for the neuromuscular disorder known as desmin-related cardio skeletal myopathy (CSM), characterized by skeletal muscle weakness |
| Immunogen | Histology Positive Control Tissue: Human prostate Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human Desmin (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
| Other Names | [desmin; Desmin; desmin; intermediate filament protein; mutant desmin p.K241E; desmin], [DES; DES; CSM1; CSM2; LGMD2R] |
| Gene, Accession # | Gene ID: 1674, NCBI: NP_001918.3, UniProt: P17661 |
| Catalog # | MBS223525 |
| Price | $550 |
| Order / More Info | Human DESMIN (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies