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Antigenic Specificity | MBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a spe |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human MBP (NP 001020271.1). |
Other Names | [myelin basic protein; Myelin basic protein; myelin basic protein; Golli-MBP; proline-rich proteoglycan 2; myelin basic protein; Myelin A1 protein; Myelin membrane encephalitogenic protein] |
Gene, Accession # | [MBP], Gene ID: 4155, NCBI: AAC41944.1, UniProt: P02686 |
Catalog # | MBS8544515 |
Price | $280 |
Order / More Info | MBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |