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Antigenic Specificity | Atg4A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunhistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Atg4A Antibody detects endogenous levels of total Atg4A. The cysteine protease Atg4 is pivotal to autophagosome membrane generation and regulation. Atg4 primes the Atg8 homologue for lipidation by cleaving its carboxy terminus and exposing its glycine residue for E1-like enzyme Atg7. The Atg8 homologue is transferred to the E2-like enzyme Atg3 before forming the Atg8-PE conjugate. During later stages of autophagy, Atg4 can reverse this lipidation event by cleaving PE, thereby recycling the Atg8 homologue. |
Immunogen | Immunogen: A synthesized peptide derived from human Atg4A |
Other Names | [Apg4a; ATG4A; Atg4al; AUT like 2 cysteine endopeptidase; Autl2; Autophagin 2; Autophagin-2; Autophagy related 4A cysteine peptidase] |
Gene, Accession # | [Atg4A], Gene ID: 115201, NCBI: NP_001308216.1, UniProt: Q8WYN0 |
Catalog # | MBS4751091 |
Price | $335 |
Order / More Info | Atg4A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |