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Antigenic Specificity | Human ESTROGEN RECEPTOR BETA 5 |
Clone | [5/25] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti human estrogen receptor beta 5, clone 5/25 specifically recognizes human estrogen receptor beta 5 (ERB5), a splice variant of the nuclear receptor hormone ERbeta (ESR2), shown to exist in at least five isoforms (ERB1-ERB5)(Moore et al. 1998). Although only the ERB1 variant appears fully functional, the remaining isoforms have been shown to form heterodimers with ERB1, thereby enhancing transcription (Shaaban et al. 2008). Immunohistochemical studies have revealed a ubiquitous expression of ERB5 in normal colorectal tissue, and to be present in all primary colorectal carcinomas studied, see Wong, N. et al. for details. The detection of estrogen (ER) and progesterone (PR) receptors using immunohistochemical staining of formal fixed |
Immunogen | n/a |
Other Names | [estrogen receptor beta isoform 2; Estrogen receptor beta; estrogen receptor beta; estrogen receptor beta 4; nuclear receptor subfamily 3 group A member 2; estrogen receptor 2 (ER beta); Nuclear receptor subfamily 3 group A member 2], [ESR2; ESR2; Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA; ESTRB; NR3A2; ER-beta] |
Gene, Accession # | Gene ID: 2100, NCBI: NP_001035365.1, UniProt: Q92731 |
Catalog # | MBS219170 |
Price | $780 |
Order / More Info | Human ESTROGEN RECEPTOR BETA 5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |