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Antigenic Specificity | IFITM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-133 of human IFITM3 (NP 066362.2). |
Other Names | [1-8U; IP15; DSPA2b] |
Gene, Accession # | [IFITM3], Gene ID: 10410, NCBI: Q01628.2, UniProt: Q01628 |
Catalog # | MBS8548807 |
Price | $280 |
Order / More Info | IFITM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |