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Antigenic Specificity | LXR alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LXR alpha Antibody detects endogenous levels of total LXR alpha. Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. |
Immunogen | Immunogen: A synthesized peptide derived from human LXR alpha |
Other Names | [Liver X receptor alpha; LXR a; LXRA; NR1H3; RLD1] |
Gene, Accession # | [LXR alpha], Gene ID: 10062, NCBI: NP_001123573.1, UniProt: Q13133 |
Catalog # | MBS4750902 |
Price | $335 |
Order / More Info | LXR alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |