Edit |   |
---|---|
Antigenic Specificity | GFRA2 (C-term), 361-390 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.47 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This GFRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human GFRA2. Glial cell line-derived neurotrophic factor (GDNF) andneurturin (NTN) are two structurally related, potent neurotrophicfactors that play key roles in the control of neuron survival anddifferentiation. The protein encoded by this gene is a member ofthe GDNF receptor family. It is aglycosylphosphatidylinositol(GPI)-linked cell surface receptor forboth GDNF and NTN, and mediates activation of the RET tyrosinekinase receptor. This encoded protein acts preferentially as areceptor for NTN compared to its other family member, GDNF familyreceptor al |
Immunogen | n/a |
Other Names | [GDNF family receptor alpha-2; GDNF receptor alpha-2; GDNFR-alpha-2; GFR-alpha-2; GDNF receptor beta; GDNFR-beta; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; RET ligand 2; TGF-beta-related neurotrophic factor receptor 2; GFRA2; GDNFRB; RETL2; TRNR2] |
Gene, Accession # | [GFRA2], Gene ID: 2675, NCBI: NP_001158510.1, UniProt: O00451 |
Catalog # | MBS9214136 |
Price | $165, $370 |
Order / More Info | GFRA2 (C-term), 361-390 Antibody from MYBIOSOURCE INC. |
Product Specific References | Souza, R.P., et al. J Psychiatr Res 44(11):700-706(2010) Souza, R.P., et al. Psychopharmacology (Berl.) 210(3):347-354(2010) Buysschaert, I.D., et al. Allergy 65(5):616-622(2010) Lavedan, C., et al. Mol. Psychiatry 14(8):804-819(2009) Volpi, S., et al. J Clin Psychiatry 70(6):801-809(2009) |