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Antigenic Specificity | NRG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of MCF7 cell lysate using NRG1 antibody. Heregulin (HRG), also called neuregulin (NRG1), neu differentiation factor (NDF) or glial growth factor-2 (GGF-2), is a soluble growth factor synthesized as a transmembrane precursor molecule. Metalloproteinases and other proteases catalyze the cleavage of its extracellular domain which is then released and functions as a ligand for ErbB3 and ErbB4 receptor tyrosine kinase. The signaling pathways of HRG-ErbB3/ErbB4 are involved in regulation of cell proliferation, differentiation, invasion, and survival of both normal and malignant tissues (1, 2). Abnormality of HRG-ErbB signaling leads to development of a variety of human diseases.HRG family has four isoforms inclu |
Immunogen | Immunogen: Recombinant protein of human NRG1 |
Other Names | [NRG1, partial; Pro-neuregulin-1, membrane-bound isoform; pro-neuregulin-1, membrane-bound isoform; neuregulin 1; Neuregulin-1Alternative name(s):Acetylcholine receptor-inducing activity; ARIA], [NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG] |
Gene, Accession # | [NRG1], Gene ID: 3084, NCBI: CAG29284.1 |
Catalog # | MBS419458 |
Price | $385 |
Order / More Info | NRG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |