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Antigenic Specificity | TIP60 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, chimpanzee, orangutan, horse, dog, mouse, bovine, rat, opossum, zebrafish, Xenopus |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect TIP60 (a HAT) in Human, Chimpanzee, Orangutan, Equine, Canine, Mouse, Bovine, Rat, Opossum, Zebrafish and Xenopus samples. Background: TIP60, originally isolated as an HIV-1 TAT-interactive protein, is known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and targets it for degradation. It belongs to the MYST family of histone acetyltransferases (HATs). TIP60 is a catalytic subunit of the NuA4 HAT complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. A co-regulator of transcription factors, TIP60 either promotes or suppresses tumorigenesis. TIP60 is an enzyme that has a role in DNA repair and apoptosi |
Immunogen | Immunogen: Synthetic peptide within the region of human TIP60 amino acids 480-530. Positive Control: Western blot: Human brain lysate, mouse brain lysate, rat brain lysate |
Other Names | [Lysine Acetyltransferase 5; KAT5], [KAT5; KAT5; TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; ZC2HC5; HTATIP1; HTATIP; TIP60; Tip60; HIV-1 Tat interactive protein] |
Gene, Accession # | [TIP60], Gene ID: 10524, NCBI: NP_001193762.1, UniProt: Q92993 |
Catalog # | MBS840492 |
Price | $270 |
Order / More Info | TIP60 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |