Edit |   |
---|---|
Antigenic Specificity | MBP (myelin basic protein) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total MBP(myelin basic protein) protein. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modific |
Immunogen | Immunogen: Peptide sequence around aa.291~295(G-G-R-D-S |
Other Names | [MGC99675] |
Gene, Accession # | [MBP], Gene ID: 4155, NCBI: NP_001020252.1, UniProt: P02686 |
Catalog # | MBS8511704 |
Price | $290 |
Order / More Info | MBP (myelin basic protein) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |