Ankyrin R Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Ankyrin R |
| Clone | [S388A-10] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2B |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~200 kDa. Does not cross-react with Ankyrin-B or Ankyrin-G. Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane. Ankyrin R, or Ank1, was first discovered in erythrocyres, but has since also been located in the brain and muscles. Mutations are associated with hereditary spehrocytosis and alzheimer's diease (2). |
| Immunogen | Immunogen: Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R |
| Other Names | [Mouse Human Ankyrin R IgG2B; Ankyrin R : APC/Cy7; Ankyrin-R; Ankyrin-1; Erythrocyte Ankyrin; ANK-1; ANK; rCG_43073; Ankyrin R] |
| Gene, Accession # | Gene ID: 286, NCBI: NP_000028.3, UniProt: P16157 |
| Catalog # | MBS8003604 |
| Price | $510 |
| Order / More Info | Ankyrin R Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 1353-92. 2. Genes and mapped phenotypes. (n.d.). Retrieved April 21, 2015. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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