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Antigenic Specificity | PARK8 (LRRK2) (L893), 878-909 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PARK8(LRRK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 878-909 amino acids from human PARK8(LRRK2). Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson's disease identified to date. LRRK2, a genetic mutation, was recently found linked to about 5 percent of inherited cases of Parkinson's disease. By high-resolution recombination mapping and candidate gene sequencing in 46 families, 6 disease-segregating mutations (5 missense and 1 putative splice site mutation). It may be central to the pathoge |
Immunogen | n/a |
Other Names | [Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin; LRRK2; PARK8] |
Gene, Accession # | [LRRK2], Gene ID: 120892, NCBI: NP_940980.3, UniProt: Q5S007 |
Catalog # | MBS9202934 |
Price | $165, $370 |
Order / More Info | PARK8 (LRRK2) (L893), 878-909 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shen J. Neuron. 2004. 44:575. Paisan-Ruiz C, et al. Neuron. 2004. 44(4):595. Zimprich A, et al. Neuron. 2004. 44(4):601. Wszolek ZK, et al. Neurology. 2004. 62(9):1619. Park YJ, et al. Transplant Proc. 2004. 36(2):353. Zimprich A, et al. Am J Hum Genet. 2004. 74:11. Bonifati V. Lancet Neurol. 2002. 1:83. Funayama M, et al.Ann Neurol. 2002. 51:296. |