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Antigenic Specificity | GABA-A-R-Beta2/3 |
Clone | 62-3G1 |
Host Species | Mouse |
Reactive Species | bovine, chicken, human, mouse, and rat |
Isotype | IgG1 |
Format | FL594 conjugate |
Size | 200 µL |
Concentration | 0.5 mg/mL |
Applications | ICC, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti-GABA-A-R-Beta2/3 monoclonal antibody, FL594 conjugated. Cross-reacts with GABA-A-R-Beta2 Does not cross-react with GABA-A-RBeta1. RRID: AB_2940218 |
Immunogen | Fraction of bovine brain GABA-A receptor affinity purified against immobilized benzodiazepine Ro7-1986/1 (1988 de Blas et al J Neurosci PMID 2828565, 1988 Vitorica et al J Neurosci PMID 2828566). Target initially identified as a GABA-A receptor by: 1). rat brain immunocytochemistry staining pattern via light microscopy identical to that seen via ligand autoradiography with 3H-muscimol; 2). immunoprecipitation of 3H-muscimol-binding activity of the purified receptor complex; 3). recognition of ~57 kDa protein in immunoblots against crude rat brain membrane fractions Binding epitope identified to be within amino acids 26-40 (QSVNDPGNMSFVKET, extracellular N-terminus, 1992 Ewert et al Brain Res, PMID 1377081) of human GABA-A-R-Beta3 (also known as Gamma-aminobutyric acid receptor subunit beta-3, accession number P28472) |
Other Names | Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) |
Gene, Accession # | GABRB3, UniProt: P28472 |
Catalog # | 75-363-FL594 |
Price | $460 |
Order / More Info | GABA-A-R-Beta2/3 Antibody from NEUROMAB |
Product Specific References | n/a |