AIF/AIFM1, Human Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityAIF/AIFM1, Human
CloneAT22E9
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a kappa
FormatProtein A purified
Size50ul, 100ul
Concentration1mg/ml (determined by BCA assay)
ApplicationsELISA, WB, ICC/IF
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DescriptionApoptosis-inducing factor 1, also known as AIFM1, is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. AIFM1 has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIFM1 from mitochondria, but not to block its apoptogenic activity. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy.
ImmunogenRecombinant human AIFM1 (98-609aa) purified from E. coli
Other NamesApoptosis-inducing factor 1 mitochondrial isoform 2 precursor, AIF, CMTX4, COWCK, COXPD6, PDCD8
Gene, Accession #NCBI: NP_665811, UniProt: O95831
Catalog #ATGA0411
Price$170, $290
Order / More InfoAIF/AIFM1, Human Antibody from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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