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Antigenic Specificity | Aldo-keto Reductase 1C1/AKR1C1, Human |
Clone | AT6D10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF, FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The human aldo-keto reductases 1C1 and 1C3 (AKR1C1 and AKR1C3) have major roles in pre receptor regulation of progesterone action. They can both convert progesterone to the less potent efficiencies. AKR1C1 and AKR1C3 also act as 3-ketosteroid reductase, and as such they can convert the most potent androgen 5alpha-DHT into 3beta-andorstandiol, which is an estrogen receptor beta ligand, and into the inactive androgen 3alpha-androstnionl, respectively. |
Immunogen | Recombinant human AKR1C1 (1-323aa) purified from E. coli |
Other Names | Aldo-keto reductase family 1 member C1, DDH1, DDH, MBAB, DD1, HAKRC, Dihydrodiol dehydrogenase 1, 20-alpha (3-alpha)-hydroxysteroid dehydrogenase, High-affinity hepatic bile acid-binding protein (HBAB) |
Gene, Accession # | NCBI: NP_001344, UniProt: Q04828 |
Catalog # | ATGA0201 |
Price | $170, $290 |
Order / More Info | Aldo-keto Reductase 1C1/AKR1C1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | Hanada N, et al. Methylation of the KEAP1 gene promoter region in human colorectal cancer. (BMC Cancer. 2012){https://pubmed.ncbi.nlm.nih.gov/22325485/} |