ASF1B, Human Antibody from NKMAX Co. Ltd.
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| Antigenic Specificity | ASF1B, Human |
| Clone | AT1D4 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b kappa |
| Format | Protein A purified |
| Size | 50ul, 100ul |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | ELISA,WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. Delivering histone H3/H4 dimers to CAF-1 or HIRA histone deposition complexes to facilitate replication-coupled and replication-independent nucleosome assembly on DNA. Both ASF1A and ASF1B are phosphorylated in S phase by the Tousled-like kinases TLK1 and TLK2, and are dephosphorylated when TLK1 and TLK2 are inactivated by Chk1 kinase in response to replicative stress. |
| Immunogen | Recombinant human ASF1B (1-202aa) purified from E. coli |
| Other Names | ASF1 anti-silencing function 1 homolog B (S.cerevisiae), CIA-II |
| Gene, Accession # | NCBI: NP_060624, UniProt: Q9NVP2 |
| Catalog # | ATGA0315 |
| Price | $170, $290 |
| Order / More Info | ASF1B, Human Antibody from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
Profile of NKMAX Co. Ltd.
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