Edit |   |
---|---|
Antigenic Specificity | ACAT1, Human |
Clone | 2C5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB,ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ACAT1 (acetyl-Coenzyme A acetyltransferase 1) is a 417 amino acid protein. ACAT1 is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. ACAT1 and ACAT2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction. Defects in ACAT1 are a cause of 3-ketothiolase deficiency. 3-ketothiolase deficiency is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded. |
Immunogen | Recombinant human ACAT1 (34-427aa) purified from E. coli |
Other Names | acetyl-CoA acetyltransferase 1, ACAT, MAT, T2, THIL |
Gene, Accession # | NCBI: NP_000010, UniProt: P24752 |
Catalog # | ATGA0583 |
Price | $190, $320 |
Order / More Info | ACAT1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |