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Antigenic Specificity | Tollip, Human |
Clone | k1B17 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a kappa |
Format | Protein G purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB,ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors (TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAk1 to the IL-1 receptor complex and inhibits IRAk1 phosphorylation and kinase activity. |
Immunogen | Recombinant human Tollip (61-274aa) purified from E. coli |
Other Names | Toll interacting protein,IL-1RAcPIP |
Gene, Accession # | NCBI: NP_061882, UniProt: Q9H0E2 |
Catalog # | ATO0918 |
Price | $170, $290 |
Order / More Info | Tollip, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |