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Antigenic Specificity | Keratin 8/KRT8, Human |
Clone | AT3D11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG3 kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF, FACS |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. |
Immunogen | Recombinant human KRT8 (1-483aa) purified from E. coli |
Other Names | KO, Keratin type II cytoskeletal 8, Keratin 8, K8, K2C8, CYK8, CK8, CARD2 |
Gene, Accession # | NCBI: NP_002264, UniProt: P05787 |
Catalog # | ATGA0253 |
Price | $170, $290 |
Order / More Info | Keratin 8/KRT8, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |