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Antigenic Specificity | Estrogen Receptor beta |
Clone | 6A12 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein G purified |
Size | 100ug |
Concentration | lot specific |
Applications | WB, ICC/IF, ChIP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Estrogen Receptor beta Mouse Monoclonal Antibody. This antibody recognizes human ER-b, a novel receptor (approx. 52 kD) recently isolated from testis. The size and structure of ER-b are very similar to ER-alpha with the ligand and DNA binding domains being highly conserved. The N-terminus of each receptor, which serves as their transactivation domain, are significantly different. Like ER-alpha, ER-b binds to estrogen with a high affinity and regulates estrogen-specific gene activation through direct interaction with estrogen response elements. |
Immunogen | 6-His fusion protein containing the region encoding aa 1-153 of human estrogen receptor-b (ER-b) expressed in E. coli. |
Other Names | ER-beta, Nuclear receptor subfamily 3 group A member 2 |
Gene, Accession # | ESR2, UniProt: Q92731, Gene ID: 2100, Accession: NP_001035365 |
Catalog # | 3336 |
Price | $503 |
Order / More Info | Estrogen Receptor beta Antibody from QED BIOSCIENCE INC. |
Product Specific References | n/a |