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Antigenic Specificity | SH3BP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-SH3BP4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SH3BP4 from other sources has not been determined. SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist. |
Immunogen | Anti-SH3BP4 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide from near the C-terminus of human SH3BP4. |
Other Names | SH3BP4 Antibody, TTP, BOG25, EHB10, TTP, SH3 domain-binding protein 4, EH-binding protein 10 |
Gene, Accession # | SH3BP4, Gene ID: 23677, NCBI: NP_055336, UniProt: Q9P0V3 |
Catalog # | 600-401-EH7 |
Price | $475 |
Order / More Info | SH3BP4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |