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Antigenic Specificity | Neurofilament L |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat, bovine, chicken |
Isotype | n/a |
Format | IgY fraction |
Size | 100 µL |
Concentration | n/a |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NF-L antibody is directed against NF-L protein. The antibody is a total IgY fraction. This antibody works well on frozen sections, cells in tissue culture and on mildly formalin fixed histological sections. Expect reactivity with the following species based on sequence homology: chicken, human, mouse, rat. Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease. Anti-Neurofilament L antibody is ideal for investigators involved in Cell Signaling and Neuroscience research. |
Immunogen | Anti-Neurofilament L Antibody was produced by repeated immunizations with preparations of bovine spinal cord intermediate filaments. |
Other Names | Neurofilament light polypeptide, NF-L, 68 kDa neurofilament protein, Neurofilament triplet L protein |
Gene, Accession # | NEFL, Gene ID: 4747, UniProt: P02548.3 |
Catalog # | 200-901-D83 |
Price | $475 |
Order / More Info | Neurofilament L Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |