ADIPONECTIN Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | ADIPONECTIN |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Adiponectin Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with Adiponectin with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Adiponectin from other sources has not been determined. Adiponectin antibody detects human adiponectin. Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike the CTRPs, which are expressed in a wide variety of tissues, adiponectin is reported to be expressed exclusively by differentiated adipocytes. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It is present in high levels in normal human plasma, but is reduced in obese subjects and often in those with increased insulin resistance and type 2 diabetes, suggesting that adiponectin may be a useful pharmacological target in various metabolic diseases. Anti-Adiponectin antibodies are ideal for investigators involved in glucose energy metabolism and apolipoprotein research. |
| Immunogen | Adiponectin Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide near the n-terminus of human adiponectin. |
| Other Names | ACDC, ACRP30, APM1, GBP28 |
| Gene, Accession # | ADIPOQ, Gene ID: 9370, NCBI: NP_004788, UniProt: Q15848 |
| Catalog # | 600-401-G73 |
| Price | $475 |
| Order / More Info | ADIPONECTIN Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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