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Antigenic Specificity | A20 |
Clone | 59A426 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-A20 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-A20 from Human, Mouse and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-A20 from other sources has not been determined. Anti-A20 antibody detects human A20. A20 (TNFAIP3) is an important regulator of proinflammatory signaling pathways, including NK-kB signaling. A20 is upregulated through NF-kB (p50/p55) activation, and subsequently down regulates NF-kB through its dual function as a deubiquitinase and ubiquitin ligase. The A20 monoclonal antibody has been instrumental in discovering various nuances of NF-kB regulation and key to defining A20 biology. Anti-A20 antibody is ideal for investigators involved in NFkappaB and Signaling research. |
Immunogen | A20 Antibody was produced in mice by repeated immunizations with recombinant human A20 protein at the c-terminus. |
Other Names | OTUD7C, Tumor necrosis factor alpha-induced protein 3, TNF alpha-induced protein 3, OTU domain-containing protein 7C, A20p50, A20p37 |
Gene, Accession # | TNFAIP3, Gene ID: 7128, NCBI: NP_001257436.1, UniProt: P21580 |
Catalog # | 200-301-H52 |
Price | $569 |
Order / More Info | A20 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |