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Antigenic Specificity | TLR8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This affinity-purified antibody is directed against human TLR8 protein. The product is affinity chromatography purified via peptide column. A BLAST analysis was used to suggest cross reactivity with TLR8 protein from human and mouse sources based on 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known. TLR8 (Toll Like Receptor 8). Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments (6) and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA (7). Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8). |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human TLR8 protein. |
Other Names | CD 288 antibody, CD288 antibody, CD288 antigen antibody, MGC119599 antibody, MGC119600 antibody, TLR 8 antibody, Toll Like Receptor 8 antibody |
Gene, Accession # | TLR8, Gene ID: 51311, NCBI: 74054102, UniProt: Q9NR97 |
Catalog # | 600-401-958 |
Price | $475 |
Order / More Info | TLR8 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |