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Antigenic Specificity | TRPV4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TRPV4 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. TRPV4 antibody is human specific. At least six isoforms of TRPV4 are known to exist. This antibody is predicted to not cross-react with other TRP protein family members. The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology: C type (canonical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD) (1). TRPV4, belongs to the V type subfamily and plays a role in systemic osmoregulation (2,3). TRPV4 is a calcium channel multi-pass membrane protein activated by various stimuli, including thermal stress, fatty acid metabolites and hypotonicity (3). TRPV4 is highly expressed in lung and kidney and widely expressed in brain. It plays an important role in regulating neural excitability (4). |
Immunogen | Anti-TRPV4 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the internal region of human TRPV4. |
Other Names | TRPV4 Antibody, SMAL, VRL2, CMT2C, SPSMA, TRP12, VROAC, HMSN2C, OTRPC4, SSQTL1, Transient receptor potential cation channel subfamily V member 4, Osm-9-like TRP channel 4, TrpV4 |
Gene, Accession # | TRPV4, Gene ID: 59341, NCBI: NP_001170899.1, UniProt: Q9HBA0 |
Catalog # | 600-401-FQ7 |
Price | $475 |
Order / More Info | TRPV4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |