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Antigenic Specificity | DOK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-DOK1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with DOK1 from other sources has not been determined. Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56dok. |
Immunogen | Anti-DOK1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the C-terminus of human DOK1. |
Other Names | DOK1 Antibody, TP1, TLP1, p240, TROVE1, VAULT2, Docking protein 1, Downstream of tyrosine kinase 1 |
Gene, Accession # | DOK1, Gene ID: 7011, NCBI: AAC51127, UniProt: Q99704 |
Catalog # | 600-401-AW9 |
Price | $475 |
Order / More Info | DOK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |