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Antigenic Specificity | GABARAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-GABARAP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Multiple isoforms of GABARAP exist due to alternative splicing events. Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy. |
Immunogen | Anti-GABARAP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the N-terminus of human GABARAP. |
Other Names | GABARAP Antibody, MM46, ATG8A, GABARAP-a, FLC3B, HT004, Gamma-aminobutyric acid receptor-associated protein, MM46 |
Gene, Accession # | GABARAP, Gene ID: 11337, NCBI: NP_009209, UniProt: O95166 |
Catalog # | 600-401-BJ0 |
Price | $475 |
Order / More Info | GABARAP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |