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Antigenic Specificity | Slitrk2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Slitrk2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is predicted to have no cross-reactivity to other Slitrk proteins. SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist. |
Immunogen | Anti-Slitrk2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide from near the C-terminus of human Slitrk2. |
Other Names | Slitrk2 Antibody, CXorf2, SLITL1, CXorf2, KIAA1854, UNQ9197/PRO34756, SLIT and NTRK-like protein 2 |
Gene, Accession # | SLITRK2, Gene ID: 84631, NCBI: Q9H156, UniProt: Q9H156 |
Catalog # | 600-401-EQ1 |
Price | $475 |
Order / More Info | Slitrk2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |