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Antigenic Specificity | AKAP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-AKAP4 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. AKAP4 antibody is human specific. At least three isoforms are known to exist; this antibody will detect the two longest isoforms. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell (1). AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm (2). It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways (2). AKAP4 has also been postulated to be a potential biomarker for breast cancer (3). |
Immunogen | Anti-AKAP4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the N-terminus of human AKAP4. |
Other Names | A-kinase anchor protein 4, AKAP-4, AKAP82, hAKAP82, CT99, FSC1, HI, PRKA4 |
Gene, Accession # | AKAP4, Gene ID: 8852, NCBI: NP_003877, UniProt: Q5JQC9 |
Catalog # | 600-401-X94 |
Price | $475 |
Order / More Info | AKAP4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |