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Antigenic Specificity | ZC3HAV1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZC3HAV1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ZC3HAV1 from other sources has not been determined. The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses. |
Immunogen | Anti-ZC3HAV1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the C-terminus of human ZC3HAV1. |
Other Names | ZC3HAV1 Antibody, ZAP, ZC3H2, ARTD13, PARP13, FLB6421, ZC3HDC2, PRO1677, Zinc finger CCCH-type antiviral protein 1, ADP-ribosyltransferase diphtheria toxin-like 13 |
Gene, Accession # | ZC3HAV1, Gene ID: 56829, NCBI: NP_064504.2, UniProt: Q7Z2W4 |
Catalog # | 600-401-GC8 |
Price | $475 |
Order / More Info | ZC3HAV1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |