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Antigenic Specificity | ATMIN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ATMIN antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist. The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3). |
Immunogen | Anti-ATMIN antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the N-terminus of human ATMIN. |
Other Names | ATMIN Antibody, ASCIZ, ZNF822, KIAA0431, ATM interactor, Zinc finger protein 822, ASCIZ |
Gene, Accession # | ATMIN, Gene ID: 23300, NCBI: NP_056066, UniProt: O43313 |
Catalog # | 600-401-Y90 |
Price | $475 |
Order / More Info | ATMIN Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |