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Antigenic Specificity | TLR11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | IgG fraction |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IgG fraction antibody is directed against mouse TLR11 protein. This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. This antibody is reactive with TLR11 from mouse sources. Cross reactivity with TLR11 from other sources has not been determined. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptibility to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of mouse toll-like receptor 11 (TLR11) protein. |
Other Names | hgnc31753 antibody, Toll-like receptor 11 antibody, Tlr11, Gm287, Toll-like receptor 12, Tlr12 |
Gene, Accession # | Tlr11, Gene ID: 239081, NCBI: 45429992, UniProt: Q6R5P0 |
Catalog # | 200-401-A66 |
Price | $475 |
Order / More Info | TLR11 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |