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Antigenic Specificity | F4/80 |
Clone | BM8.1 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | fluorescein (FITC) conjugate |
Size | 500 µg |
Concentration | 0.5mg/mL |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Fluorescein conjugated F4/80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse F4/F80. Cross reactivity with F4/F80 from other sources has not been tested. Anti-F4/F80 is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. The BM8.1 antibody is specific for mouse F4/80 antigen, a 125 kDa transmembrane protein widely expressed by members of the mononuclear phagocyte system and considered to be a key marker for mature macrophage cells. F4/80 is differentially expressed during myeloid cell development, and may be regulated by certain cytokines within the tissue microenvironment. Other cell types shown to express this antigen include Langerhans cells, Kupffer cells and dendritic cell subsets. BM8.1 is widely used together with antibodies to CD115 (c-fms), CD11b and CD11c to identify myeloid / macrophage cells by flow cytometry. |
Immunogen | Anti-F4/80 Antibody (Monoclonal) was produced by repeated immunizations with F4/80 antigen. |
Other Names | EMR1, Ly71, EGF-TM7, Adhesion G protein-coupled receptor E1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor, Gpf480, Adgre1 |
Gene, Accession # | Adgre1, Gene ID: 13733, NCBI: NP_034260.1, UniProt: Q61549 |
Catalog # | 200-502-L55 |
Price | $569 |
Order / More Info | F4/80 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |