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Antigenic Specificity | ZNF521 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZNF521 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. ZNF521 antibody is human specific. The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis. |
Immunogen | Anti-ZNF521 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the N-terminus of human ZNF521. |
Other Names | ZNF521 Antibody, EHZF, Evi3, EHZF, LIP3, Zinc finger protein 521, Early hematopoietic zinc finger protein |
Gene, Accession # | ZNF521, Gene ID: 25925, NCBI: NP_001295154.1, UniProt: Q96K83 |
Catalog # | 600-401-GG3 |
Price | $475 |
Order / More Info | ZNF521 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |