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Antigenic Specificity | PML |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | 0.14 mg/ml |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-PML Antibody was purified by affinity purification. Cross reactivity with other species was not tested. PML is a transcription factor and tumor suppressor which belongs to the tripartite motif (TRIM) family. This motif contains three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML regulates the response of p53 to oncogenic signals. It is often involved in a chromosomal translocation between chromosomes 15 and 17 which results in a PML/RARalpha fusion protein and is associated with most cases of acute promyelocytic leukemia. Anti-PML Antibody is ideal for research in Gene Expression, Cell Cycle Control and Cancer. |
Immunogen | Anti-PML Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides from human PML. |
Other Names | Protein PML Promyelocytic leukemia protein, RING finger protein 71, Tripartite motif-containing protein 19, MYL, PP8675, RNF71, TRIM19 |
Gene, Accession # | PML, Gene ID: 5371, NCBI: NP_002666.1, UniProt: P29590 |
Catalog # | 600-401-X44 |
Price | $445 |
Order / More Info | PML Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |