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Antigenic Specificity | F1A alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-F1A alpha Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with F1A alpha from other sources has not been determined. Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1b. F1Aalpha/FEM1b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues. |
Immunogen | Anti-F1A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the C-terminus of human F1A. |
Other Names | F1A alpha Antibody, F1AA, F1A-ALPHA, FEM1-beta, F1AA, KIAA0396, Protein fem-1 homolog B, FEM1b |
Gene, Accession # | FEM1B, Gene ID: 10116, NCBI: AAF05314, UniProt: Q9UK73 |
Catalog # | 600-401-BC7 |
Price | $475 |
Order / More Info | F1A alpha Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |