PARP Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | PARP |
| Clone | 194C1439 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b kappa |
| Format | Protein G purified |
| Size | 100 µg |
| Concentration | 0.5 mg/mL |
| Applications | Flow Cytometry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-PARP Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-PARP from human based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-PARP from other sources has not been determined. Anti-PARP antibody detects human PARP. The poly (ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as methylation of N3-adenine, which activates the base excision repair process. PARP [Poly (ADP-ribose) polymerase] is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa-fragment irreversibly bind to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks. Anti-PARP antibody is ideal for investigators involved in Apoptosis, DNA damage and Repair research. |
| Immunogen | PARP Antibody was produced in mice prepared by repeated immunizations with a peptide containing amino acids near the 214/215 cleavage site of human PARP protein. |
| Other Names | ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, PARP-1, 2.4.2.30, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1 |
| Gene, Accession # | PARP1, Gene ID: 142, NCBI: NP_001609.2, UniProt: P09874 |
| Catalog # | 200-301-I03 |
| Price | $495 |
| Order / More Info | PARP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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