APOLIPOPROTEIN B Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | APOLIPOPROTEIN B |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 1 mg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This product has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other apoLipoproteins and human serum proteins to remove any unwanted specificities. Typically less than 1% cross reactivity against other types of apoLipoprotein was detected by ELISA against purified standards. This antibody reacts with human apoLipoprotein B and has negligible cross-reactivity with Type A-I, A-II, C-I, C-II, C-III, E and J apoLipoproteins. Specific cross reaction of anti-apoLipoprotein antibodies with antigens from other species has not been determined. Non-specific cross reaction of anti-apoLipoprotein antibodies with other human serum proteins is negligible. Anti Apolipoprotein B antibody recognizes the gene product of APOB that is the primary apolipoprotein of low-density lipoproteins, which is responsible for carrying cholesterol to tissues. While it is unclear exactly what functional role APOB plays in LDL, it is the primary apolipoprotein component and is absolutely required for its formation. What is clear is that the APOB on the LDL particle acts as a ligand for LDL receptors in various cells throughout the body. Through a mechanism that is not fully understood, high levels of APOB can lead to plaques that cause vascular disease (atherosclerosis), leading to heart disease. There is considerable evidence that levels of APOB are a better indicator of heart disease and cardiovascular risk than total cholesterol or LDL. However, primarily for historic reasons, cholesterol, and more specifically, LDL-cholesterol, remains the primary lipid test for the risk factor of atherosclerosis. |
| Immunogen | apoLipoprotein Type B was isolated from human plasma by density gradient centrifugation followed by HPLC purification. |
| Other Names | goat anti-Apolipoprotein B antibody, Apo B-100, Apo B-48, APOB protein antibody, Apolipoprotein-B 100 antibody, Apolipoprotein B 48 antibody, Apolipoprotein B antibody, FLDB antibody |
| Gene, Accession # | APOB, Gene ID: 338, NCBI: AAH51278.1, UniProt: Q7Z7Q0 |
| Catalog # | 600-101-111 |
| Price | $1285 |
| Order / More Info | APOLIPOPROTEIN B Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 11145938 // 23756663 // 24838241 // 24907293 // 25970332 // 27729393 // 30243490 // 30692541 // 30862813 // 31526472 // 33054837 // 33586702 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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