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Antigenic Specificity | MAP1LC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MAP1LC3 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. MAP1LC3 antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3 are known to exist. MAP1LC3 antibody is predicted to detect MAP1LC3A, MAP1LC3B, and MAP1LC3C. Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3 is a subfamily of three related proteins belonging to the MAP1 LC3 family and it includes MAP1LC3A, MAP1LC3B, and MAP1LC3C (2). MAP1LC3 is the mammalian homolog of yeast ATG8 and is essential for autophagy and associated with the autophagosome membranes after processing (3). The three isoforms exhibit distinct expression patterns and both MAP1LC3A and MAP1LC3B but not MAP1LC3B, are post-translationally modified, suggesting the three isoforms may have different physiological functions (4). |
Immunogen | Anti-MAP1LC3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 12 amino acid peptide near the internal region of human MAP1LC3A. |
Other Names | MAP1LC3 Antibody, LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3Autophagy-related protein LC3 A |
Gene, Accession # | MAP1LC3A, Gene ID: 84557, NCBI: NP_115903, UniProt: Q9H492 |
Catalog # | 600-401-CQ4 |
Price | $475 |
Order / More Info | MAP1LC3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |