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Antigenic Specificity | MAP1LC3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MAP1LC3A antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. MAP1LC3A antibody is human specific. At least two isoforms of MAP1LC3A are known to exist. MAP1LC3A antibody is predicted to not cross-react with MAP1LC3B or MAP1LC3C. Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3A belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3A is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3A, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3). |
Immunogen | Anti-MAP1LC3A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 10 amino acid peptide near the N-terminus of human MAP1LC3A. |
Other Names | MAP1LC3A Antibody, LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3Autophagy-related protein LC3 A |
Gene, Accession # | MAP1LC3A, Gene ID: 84557, NCBI: NP_852610, UniProt: Q9H492 |
Catalog # | 600-401-CQ5 |
Price | $475 |
Order / More Info | MAP1LC3A Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |