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Antigenic Specificity | Histone H3 K27 me1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | 1.93 mg/ml |
Applications | ELISA, Chip, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Histone H3 k27 me1 Antibody was purified by affinity purification. This product reacts with human Histone 3 methyl Lys27. Cross reactivity with H3K27me1 from species other than human is not known. Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called ``histone code''. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Anti-Histone H3 K27 me1 Antibody is ideal for research in Chromatin Remodeling and Genetics. |
Immunogen | Anti-Histone H3 K27 me1 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide of histone H3 containing the monomethylated lysine 27. |
Other Names | Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/e, Histone H3/f, Histone H3/g, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l |
Gene, Accession # | HIST1H3A, Gene ID: 3020, NCBI: NP_002098, UniProt: P84243 |
Catalog # | 600-401-W54 |
Price | $475 |
Order / More Info | Histone H3 K27 me1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |