Edit |   |
---|---|
Antigenic Specificity | GAP43 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | IgY fraction |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-GAP-43 Antibody is a purified total IgY fraction. GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone. GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C modulates the interaction of GAP-43 with actin and may also affect neurotransmitter release during forms of plasticity like LTP. GAP-43 Antibody is ideal for researchers interested in neuroscience research. |
Immunogen | Anti-GAP-43 Antibody was produced in chickens by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GAP43 conjugated to KLH. |
Other Names | Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43, Protein F1 |
Gene, Accession # | Gap43, Gene ID: 29423, NCBI: NP_058891.1, UniProt: P07936 |
Catalog # | 200-901-X10 |
Price | $475 |
Order / More Info | GAP43 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |