GABA(A) Receptor gamma 2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | GABA(A) Receptor gamma 2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat |
| Isotype | n/a |
| Format | serum |
| Size | 50 µL |
| Concentration | Titrated value sufficient to run approximately 10 mini blots. |
| Applications | Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-GABA(A) Receptor gamma 2 Antibody is directed against rat GABA(A) Receptor gamma 2. The antibody was prepared from monospecific neat serum. Expect reactivity with the following species based on 100% sequence homology: chicken, human, mouse, non-human primate, zebra fish. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) sub-type. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six αs, four βs and four γs, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for α- and β-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, co-expression of a γ-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor. Phosphorylation of β-subunits of the receptor has been shown to modulate GABAA-R function. Anti-GABA(A) Receptor gamma 2 antibody is ideal for investigators involved in Neuroscience. |
| Immunogen | Anti-GABA(A) Receptor gamma 2 Antibody was produced by repeated immunizations with rat GABA(A) Receptor gamma 2- Synthetic peptide corresponding to amino acid residues specific to the gamma 2 subunit. |
| Other Names | rabbit anti-GABA(A) Receptor gamma 2 Antibody, Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, Gabrg2 |
| Gene, Accession # | Gabrg2, Gene ID: 29709, NCBI: NP_899156.1, UniProt: P18508.1 |
| Catalog # | 112-401-C81 |
| Price | $475 |
| Order / More Info | GABA(A) Receptor gamma 2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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