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Antigenic Specificity | Herpes Simplex Virus Type II |
Clone | DBM15.69 |
Host Species | Mouse Balb/c |
Reactive Species | herpesvirus |
Isotype | IgG1 |
Format | unconjugated |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody is supplied as a purified immunoglobulin. This antibody reacts with herpes simplex virus type 2. It is specific for the viral glycoprotein D (gD) protein. Herpes simplex type 2 (HSV2) belongs to a family that includes HSV1, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus. HSV1 and HSV2 are extremely difficult to distinguish from each other. The HSV-1 strain generally appears in the orafacial organs. HSV2 usually resides in the sacral ganglion at the base of the spine. These viruses have a large DNA genome, capsid, and a lipid bilayer membrane derived from the nuclear membrane of the last host. These viruses are capable of entering a latent phase where the host shows no visible sign of infection. Envelope glycoprotein C (gC) and glycoprotein B (gB) bind to cell surface partials heparin sulfate. Receptor binding protein glycoprotein D (gD) binds to HVEM, nectin-1, and 3-O sulfated heparin sulfate forming complexes with glycoprotein H (gH) and glycoprotein (gL) creating an entry pore for the viral capsid. |
Immunogen | Anti-Herpes Simplex Virus Type II (HSV2) antibody was produced in BALB/C mice by repeated immunizations with Parker strain of herpes simplex virus type 2. |
Other Names | Herpes, Herpesvirus, Simplex, HSV, HSV2 |
Gene, Accession # | gD |
Catalog # | Mob542-01 |
Price | $485 |
Order / More Info | Herpes Simplex Virus Type II Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |