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Antigenic Specificity | ZIP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZIP6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ZIP6 from other sources has not been determined. The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway. |
Immunogen | Anti-ZIP6 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the internal region of human ZIP6. |
Other Names | ZIP6 Antibody, LIV-1, LIV1, ZIP6, Zinc transporter ZIP6, Estrogen-regulated protein LIV-1, ZIP-6 |
Gene, Accession # | SLC39A6, Gene ID: 25800, NCBI: NP_001092876.1, UniProt: Q13433 |
Catalog # | 600-401-GF1 |
Price | $475 |
Order / More Info | ZIP6 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |