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Antigenic Specificity | POU3F2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-POU3F2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms are known to exist. This antibody will recognize both isoforms. POU3F2 antibody is predicted to not cross-react with other members of the POU domain class 3 family. POU3F2, also commonly known as brain-2, is a member of a family of POU domain genes expressed in mouse brain and is thought to be involved in the development of the neocortex and establishment of neural cell lineage. Recent studies suggest that POU3F2 may be involved with the development of neurodegenerative diseases as well as tumor development and proliferation. Along with the neural-lineage-specific transcription factors ASCL1 and MYT1L, POU3F2 can convert fibroblasts to functional neurons in vitro, a form of artificial stem cells termed induced neuronal (iN) cells, suggesting that these cells may be useful in the treatment of neurodegenerative diseases. |
Immunogen | Anti- POU3F2 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human POU3F2. |
Other Names | POU3F2 Antibody, BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7, N-Oct3, BRN2, POU domain, class 3, transcription factor 2, Nervous system-specific octamer-binding transcription factor N-Oct-3, Brain-2 |
Gene, Accession # | POU3F2, Gene ID: 5454, NCBI: NP_005595, UniProt: P20265 |
Catalog # | 600-401-DR4 |
Price | $475 |
Order / More Info | POU3F2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |